This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Most early life epilepsies are treated within an “evidence-free practice zone,”1 and many seizure therapies have seeped into practice without thorough vetting in studies designed under traditional standards for evidence-based medicine. In this issue of Neurology®, Treadwell2 and Tsou3 present formal systematic reviews of literature published since 1999 for the effectiveness of and “harm” from antiseizure medications (ASMs) and dietary therapies2 and epilepsy surgery3 in children younger than 36 months. Their conclusions echo those of the 2015 International League Against Epilepsy working group that there is little evidence to direct current treatment practices.4 This is a tough and worthy topic. We agree with the authors' conclusions on the main point but differ on others.
Footnotes
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.
↵* These authors contributed equally.
See page 16
See page 17
- Received July 7, 2022.
- Accepted in final form August 10, 2022.
- © 2022 American Academy of Neurology
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
