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April 27, 2004; 62 (8) Brief Communications

Nimodipine for treatment of primary thunderclap headache

S. -R. Lu, Y. -C. Liao, J. -L. Fuh, J. -F. Lirng, S. -J. Wang
First published April 26, 2004, DOI: https://doi.org/10.1212/01.WNL.0000120669.85649.77
S. -R. Lu
From the Department of Neurology (Dr. Lu), Kaohsiung Medical University, Chung-Ho Memorial Hospital, Neurological Institute (Drs. Liao, Fuh, and Wang) and Department of Radiology (Dr. Lirng), Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine (Drs. Liao, Fuh, Lirng, and Wang), Taiwan.
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Y. -C. Liao
From the Department of Neurology (Dr. Lu), Kaohsiung Medical University, Chung-Ho Memorial Hospital, Neurological Institute (Drs. Liao, Fuh, and Wang) and Department of Radiology (Dr. Lirng), Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine (Drs. Liao, Fuh, Lirng, and Wang), Taiwan.
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J. -L. Fuh
From the Department of Neurology (Dr. Lu), Kaohsiung Medical University, Chung-Ho Memorial Hospital, Neurological Institute (Drs. Liao, Fuh, and Wang) and Department of Radiology (Dr. Lirng), Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine (Drs. Liao, Fuh, Lirng, and Wang), Taiwan.
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J. -F. Lirng
From the Department of Neurology (Dr. Lu), Kaohsiung Medical University, Chung-Ho Memorial Hospital, Neurological Institute (Drs. Liao, Fuh, and Wang) and Department of Radiology (Dr. Lirng), Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine (Drs. Liao, Fuh, Lirng, and Wang), Taiwan.
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S. -J. Wang
From the Department of Neurology (Dr. Lu), Kaohsiung Medical University, Chung-Ho Memorial Hospital, Neurological Institute (Drs. Liao, Fuh, and Wang) and Department of Radiology (Dr. Lirng), Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine (Drs. Liao, Fuh, Lirng, and Wang), Taiwan.
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Citation
Nimodipine for treatment of primary thunderclap headache
S. -R. Lu, Y. -C. Liao, J. -L. Fuh, J. -F. Lirng, S. -J. Wang
Neurology Apr 2004, 62 (8) 1414-1416; DOI: 10.1212/01.WNL.0000120669.85649.77

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Abstract

Eleven patients with primary thunderclap headache (TCH) were treated with oral nimodipine 30 to 60 mg every 4 hours or IV nimodipine 0.5 to 2 mg/h if the oral regimen failed or images showed cerebral vasospasm. With oral nimodipine, headache did not recur in the nine patients without vasospasm. IV nimodipine was given in two patients with vasospasm, including one who developed ischemic stroke. Nimodipine may be effective for TCH. Vasospasm may warrant IV nimodipine.

  • Received October 17, 2003.
  • Accepted in final form December 16, 2003.
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