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April 27, 2004; 62 (8) Clinical/Scientific Notes

Auditory dysfunction in chronic inflammatory demyelinating polyradiculoneuropathy

Gerald J.D. Hengstman, Helenius J. Schelhaas, Machiel J. Zwarts
First published April 26, 2004, DOI: https://doi.org/10.1212/01.WNL.0000120662.29421.46
Gerald J.D. Hengstman
From the Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, The Netherlands.
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Helenius J. Schelhaas
From the Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, The Netherlands.
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Machiel J. Zwarts
From the Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, The Netherlands.
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Citation
Auditory dysfunction in chronic inflammatory demyelinating polyradiculoneuropathy
Gerald J.D. Hengstman, Helenius J. Schelhaas, Machiel J. Zwarts
Neurology Apr 2004, 62 (8) 1446-1448; DOI: 10.1212/01.WNL.0000120662.29421.46

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Cranial nerve involvement, most commonly affecting the facial and oculomotor nerves, has been reported in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).1,2⇓ Symptomatic involvement of the vestibulocochlear nerve has been described at least once but only in the vestibular part of the nerve.1

We describe a patient who presented with a relapse of CIDP accompanied by sudden bilateral sensorineural hearing loss. Brainstem auditory evoked potentials (BAEPs) confirmed bilateral retrocochlear dysfunction. Treatment with high-dose prednisone was associated with nearly complete recovery clinically and neurophysiologically.

Case report.

A 66-year-old man sought treatment for sudden bilateral hearing loss and paraesthesias of the lower extremities. Ten months earlier, CIDP had been diagnosed based on clinical signs and symptoms (symmetric muscle weakness, sensory ataxia, distal hypesthesia, and absent tendon reflexes), results of nerve conduction studies (i.e., motor distal latency and F waves of the ulnar and median nerves >130% of the upper limit of normal, slowing of nerve conduction velocities in ulnar and peroneal nerves <70% of the lower limit of normal, and presence of a conduction block in the …

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  • Audition
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