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2023年6月6日 ;100 (23) 半岛体育app苹果下载

卒中后认知功能的短期轨迹

STROKOG协作研究

视图ORCID概要杰西卡·w·罗,约翰·d·克劳福德,视图ORCID概要大卫·w·德斯蒙德,视图ORCID概要Hee-Joon Bae,视图ORCID概要Jae-Sung Lim,视图ORCID概要奥利弗Godefroy,马丁尼Roussel,视图ORCID概要塞巴斯蒂安·科勒,朱莉Staals,Frans Verhey,克里斯托弗•陈,鑫徐,艾迪·j·庄,Nagaendran Kandiah,视图ORCID概要瑞吉斯朱尔茨博尔代,视图ORCID概要鲍特Dondaine,anne - marie Mendyk,亨利Brodaty,Latchezar Traykov,视图ORCID概要日本岛Mehrabian,Neli佩特洛娃,达伦·m·李普尼基,视图ORCID概要本尊盘林,视图ORCID概要Perminder s Sachdev,中风和认知(STROKOG)合作
第一次出版2023年4月18日, DOI: https://doi.org/10.1212/WNL.0000000000207281
杰西卡·w·罗
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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约翰·d·克劳福德
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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大卫·w·德斯蒙德
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Hee-Joon Bae
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Jae-Sung Lim
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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奥利弗Godefroy
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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  • Olivier Godefroy ORCID纪录
马丁尼Roussel
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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塞巴斯蒂安·科勒
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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朱莉Staals
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Frans Verhey
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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克里斯托弗•陈
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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鑫徐
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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艾迪·j·庄
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Nagaendran Kandiah
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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瑞吉斯朱尔茨博尔代
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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鲍特Dondaine
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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anne - marie Mendyk
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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亨利Brodaty
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Latchezar Traykov
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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日本岛Mehrabian
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Neli佩特洛娃
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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达伦·m·李普尼基
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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本尊盘林
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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Perminder s Sachdev
健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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健康的大脑中心的老化(CHeBA) (J.W.L.,J.D.C.,到了,D.M.L., B.C.P.L., P.S.S.), UNSW, Sydney, Australia; No affiliation (D.W.D.); Department of Neurology (H.-J.B.), Seoul National University School of Medicine, Seoul National University Bundang Hospital, Seongnam; Department of Neurology (J.-S.L.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology and Laboratory of Functional Neurosciences (O.G., M.R.), University Hospital of Amiens, France; Department of Psychiatry and Neuropsychology (S.K., F.V.), School for Mental Health and Neuroscience (MHeNs), Alzheimer Center Limburg, Maastricht University; Department of Neurology (J.S.), School for Cardiovascular diseases (CARIM), Maastricht University Medical Center (MUMC+), the Netherlands; Memory Aging and Cognition Centre (C.C., X.X., E.J.C.), Departments of Pharmacology and Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore; The Second Affiliated Hospital and School of Public Health (X.X.), Zhejiang University School of Medicine, Hangzhou, China; National Neuroscience Institute (N.K.); Duke-NUS Medical School (N.K.), Singapore; University of Lille (R.B., T.D., A.-M.M.), Inserm, CHU de Lille, Lille Neuroscience and Cognition, France; Dementia Collaborative Research Centre (H.B., P.S.S.), UNSW Medicine, UNSW, Sydney, Australia; Clinic of Neurology (L.T., S.M.), UH “Alexandrovska,” Medical University-Sofia; and Kaneff University Hospital (N.P.), Ruse, Bulgaria.
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卒中后认知功能的短期轨迹
STROKOG协作研究
杰西卡·W。罗,约翰。D。克劳福德,大卫·W。德斯蒙德,Hee-Joon英国宇航系统公司,Jae-SungLim,奥利维尔Godefroy,马丁尼Roussel,塞巴斯蒂安。科勒,朱莉Staals,弗兰斯Verhey,克里斯多夫陈,鑫徐,艾迪·J。庄,NagaendranKandiah,瑞吉斯朱尔茨博尔代,鲍特Dondaine,安妮玛丽Mendyk,亨利Brodaty,LatchezarTraykov,日本岛Mehrabian,Neli佩特洛娃,达伦·M。李普尼基,本尊盘林,Perminder年代。Sachdev,中风和认知(STROKOG)合作
半岛投注体育官网 2023年6月, One hundred. (23) e2331-e2341; DOI:10.1212 / WNL.0000000000207281

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背景和目标过去的研究对卒中后认知功能都集中在平均性能或随时间变化的,但很少有研究卒中后认知轨迹的模式。这个项目使用潜类增长分析(LCGA)确定集群的患者相似的认知成绩第一年卒中后和在多大程度上长期认知结果预测的集群(“轨迹组”)。

方法数据从中风和寻求认知财团。LCGA是用来识别集群基于标准化的全球认知得分的轨迹基线(T11年随访(T)和2)。一步个体参与者数据荟萃分析是用来分析风险因素轨迹团体和协会的轨迹组在长期随访(T与认知3)。

结果九医院卒中组1149例(男性63%;平均年龄66.4岁(标准差11.0))。中位数时间评估T1是3.6个月卒中后,在T 1.0年2,在T和3.2年3。LCGA发现3组轨迹,表现为不同的平均水平的认知成绩T1(低档次,−3.27 SD [0.94], 17%;medium-performance−1.23 SD [0.68], 48%;和高性能,0.71 SD [0.77], 35%)。认知有显著改善高性能集团(每年0.22 SD, 95%可信区间0.07 - -0.36),但低档次和medium-performance组变化不显著(−0.10每年SD, 95% CI 0.33−0.13;0.11每年SD, 95% CI 0.08−0.24,分别)。因素与低收入(vs)性能组包括年龄(相对风险比存款准备金率1.18,95% CI 1.14 - -1.23),多年的教育(存款准备金率0.61,95% CI 0.56 - -0.67)、糖尿病(存款准备金率3.78,95% CI 2.08 - -6.88),大型动脉和小血管中风(存款准备金率2.77,95% CI 1.32 - -5.83),和中度/重度中风(存款准备金率3.17,95%可信区间1.42 - -7.08)。全球认知轨迹组预测T3,但其预测能力与成绩相当T1。

讨论在一年级卒中后认知功能的轨迹是异质的。卒中后认知功能基线∼3.6个月是一个很好的预测长期的认知结果。年龄较大,低水平的教育,糖尿病,动脉中风大,和更大的中风严重性认知能力下降的风险因素在第一年。

术语表

另类投资会议=
Akaike信息标准;
ALCPP=
平均潜伏类的后验概率;
BIC=
贝叶斯信息准则;
位差=
四分位范围;
LCGA=
潜在的类增长分析;
STROKOG=
中风和认知财团

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  • 去半岛投注体育官网Neurology.org/N为充分披露。资金信息和披露认为作者相关的,如果有的话,年底提供这篇文章。

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  • 收到了2022年5月17日。
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