文摘
extratemporal的影响和颞叶皮质切除对儿童难治性癫痫原因还不是很清楚。我们评估一系列综合的结果变量连续33孩子收到癫痫手术12岁或更年轻。22(67%)孩子们控制发作,3个(9%)大于90%减少癫痫发作,和四个没有改善。抗癫痫药物(aed) 10(30%)不需要孩子和在另一个10数量减少。6(29%)的21个测试儿童改善口头或性能大于10分的智商手术后,当一个(4%)有一个言语智商的降低大于10分。一个温和的轻偏瘫和一个劣质象限盲发生;两人都是预期。我们使用了儿童健康调查问卷(CHQ),一个有效的和可靠的仪器为儿童,来评估健康相关的生活质量(HRQOL)。CHQ的六12子量表得分显著降低外科组与410年相比同龄对照组。父母满意手术28例(85%)病例。 Pathologic tissue diagnosis and site of resection were not associated significantly with any outcome measure. We conclude that surgery eliminates seizures and reduces AED requirements in most children with intractable epilepsy selected by currently available methods. Further investigation is needed to establish the nature and significance of inferior scores in the surgical group in the HRQOL domains of physical function, general health, and self-esteem.
- 美国神经病学学会©1997半岛投注体育官网
